Document Detail


Issues of recruitment and rationale for conducting clinical trials on mutans streptococci suppression in mothers.
MedLine Citation:
PMID:  20827385     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The aims of this study are (1) to describe issues related to recruitment of mothers participating in a clinical trial of transmission of mutans streptococci (MS) from mother to child in Bauru, Brazil and (2) to perform cross-cultural and temporal comparisons of levels of infection of the MS in mothers of Bauru. A total of 1422 mothers were visited at their domiciles. Cutoff levels for the MS were established at ≥10(5) CFU/mL saliva. The main reason for a mother not enrolling was not being highly infected by the MS, yet 76% of mothers presented with levels ≥10(5) CFU/mL saliva. Recent studies in industrialized countries showed a negative coefficient for linear tests indicating significant decline overtime in the levels of MS in mothers. Intercountry comparisons for mothers' salivary levels of the MS with the Bauru study as the reference revealed significant differences with studies conducted in the last two decades.
Authors:
Walter A Bretz; Odila P S Rosa; Salete M B Silva; Patricia Corby; Lisa Weissfeld; Walter J Loesche
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Publication Detail:
Type:  Journal Article     Date:  2010-08-10
Journal Detail:
Title:  International journal of dentistry     Volume:  2010     ISSN:  1687-8736     ISO Abbreviation:  Int J Dent     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-09     Completed Date:  2011-07-14     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  101524183     Medline TA:  Int J Dent     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
College of Dentistry, New York University, NY 10010, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
R01 DE013534-01A1/DE/NIDCR NIH HHS

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