Document Detail

Issues in the pathology and diagnosis of the chronic myeloproliferative disorders and the myelodysplastic syndromes.
MedLine Citation:
PMID:  8475918     Owner:  NLM     Status:  MEDLINE    
We have attempted to discuss some of the issues that interest pathologists who are involved in the diagnosis of CMPD and MDS. In most cases, correlation of the clinical findings with the findings in the blood and marrow will allow the morphologist to arrive at a proper diagnosis. Nevertheless, there will continue to be cases that are difficult to classify, or in which the clinical features are out of keeping with the morphologic features. These cases are challenging and thought-provoking, and the application of newer diagnostic techniques, such as molecular genetics, may provide important insights.
J I Dickstein; J W Vardiman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  99     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-05-17     Completed Date:  1993-05-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  513-25     Citation Subset:  AIM; IM    
University of Chicago Hospitals and Clinics, Department of Pathology, IL 60637.
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MeSH Terms
Bone Marrow Examination
Child, Preschool
Chromosome Aberrations* / genetics
Chromosome Disorders*
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 9
Chronic Disease
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / blood,  genetics,  pathology*
Middle Aged
Myelodysplastic Syndromes / blood,  pathology*
Myeloproliferative Disorders / pathology
Primary Myelofibrosis / blood,  complications,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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