Document Detail


Isradipine and the coronary circulation.
MedLine Citation:
PMID:  8480505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Isradipine has been shown to be an effective vasodilator in different vascular beds. Experimental evidence suggests that isradipine is a potent coronary vasodilator, and this is supported by clinical studies in both cardiology and cardiac surgery. Furthermore, in these studies, coronary vasodilation was not accompanied by evidence of any significant effect on cardiac contractility or conduction. It can be concluded that the cardiac effects of isradipine will ultimately prove to be beneficial in patients undergoing myocardial revascularization.
Authors:
R O Feneck; S M Underwood; R K Walesby
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica. Supplementum     Volume:  99     ISSN:  0515-2720     ISO Abbreviation:  Acta Anaesthesiol Scand Suppl     Publication Date:  1993  
Date Detail:
Created Date:  1993-05-27     Completed Date:  1993-05-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370271     Medline TA:  Acta Anaesthesiol Scand Suppl     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  38-42     Citation Subset:  IM    
Affiliation:
Department of Cardiothoracic Anaesthesia, London Chest Hospital, UK.
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MeSH Terms
Descriptor/Qualifier:
Animals
Coronary Circulation / drug effects*,  physiology
Hemodynamics / drug effects*,  physiology
Humans
Isradipine / therapeutic use*
Chemical
Reg. No./Substance:
75695-93-1/Isradipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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