Document Detail


Isotropic high-spatial-resolution contrast-enhanced 3.0-T MR angiography in patients suspected of having renal artery stenosis.
MedLine Citation:
PMID:  18270376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to prospectively evaluate the diagnostic performance of contrast material-enhanced magnetic resonance (MR) angiography performed at 3 T for assessment of renal artery stenosis (RAS) by using parallel acquisition techniques with high acceleration factors and with digital subtraction angiography (DSA) as the reference standard. The study was institutional review board approved, and written informed consent was obtained from all patients. Twenty-nine patients (18 men, 11 women; mean age, 57.1 years +/- 14.3 [standard deviation]) suspected of having RAS underwent MR angiography. Images were evaluated qualitatively and quantitatively. The interobserver variability, sensitivity, specificity, and positive and negative predictive values of 3-T MR angiography, as compared with DSA (performed in 15 patients), were calculated. All examinations yielded good or excellent image quality. The sensitivity and specificity of MR angiography in grading significant (>75%) stenosis were 94% and 96%, respectively. Owing to its high sensitivity, contrast-enhanced 3-T MR angiography can be used reliably to exclude RAS and can serve as a useful screening method in the diagnostic work-up of patients with arterial hypertension.
Authors:
Ulrich Kramer; Jakub Wiskirchen; Michael C Fenchel; Achim Seeger; Gerhard Laub; Gunnar Tepe; J Paul Finn; Claus D Claussen; Stephan Miller
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Publication Detail:
Type:  Journal Article     Date:  2008-02-12
Journal Detail:
Title:  Radiology     Volume:  247     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-28     Completed Date:  2008-04-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  228-40     Citation Subset:  AIM; IM    
Affiliation:
Department of Diagnostic Radiology, University of Tuebingen, Hoppe-Seyler-Str 3, 72076 Tuebingen, Germany. ulrich.kramer@med.uni-tuebingen.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Angiography, Digital Subtraction
Contrast Media
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Angiography*
Male
Middle Aged
Predictive Value of Tests
Renal Artery / pathology,  radiography
Renal Artery Obstruction / diagnosis*,  radiography
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Contrast Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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