| Isotretinoin therapy for antibiotic-refractory acne in Apert's syndrome. | |
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MedLine Citation:
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PMID: 10606949 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Apert's syndrome is a congenital disorder characterized by the premature fusion of the cranial sutures and early epiphyseal closure. Severe pustular acne is a common feature. We report a case that failed to respond to conventional antibiotic treatment but resolved following isotretinoin therapy. The patient's permanent tracheostomy proved a management challenge during isotretinoin treatment. The role of androgen-sensitivity is discussed in relation to the skin and bones. |
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Authors:
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A M Downs; C A Condon; R Tan |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical and experimental dermatology Volume: 24 ISSN: 0307-6938 ISO Abbreviation: Clin. Exp. Dermatol. Publication Date: 1999 Nov |
Date Detail:
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Created Date: 2000-02-11 Completed Date: 2000-02-11 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7606847 Medline TA: Clin Exp Dermatol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 461-3 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Bristol Royal Infirmary, Bristol, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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drug therapy* Acrocephalosyndactylia / complications*, genetics Anti-Bacterial Agents / therapeutic use Child Humans Isotretinoin / therapeutic use* Male Oxytetracycline / therapeutic use Treatment Failure |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 4759-48-2/Isotretinoin; 79-57-2/Oxytetracycline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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