| Isotretinoin and psychiatric illness in adolescents and young adults. | |
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MedLine Citation:
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PMID: 12841827 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the relationship between isotretinoin and psychiatric illness in adolescents and young adults. DATA SOURCES: Primary literature located via MEDLINE (1966-December 2002). Key terms were isotretinoin, depression, psychosis, suicide, and adolescents. DATA SYNTHESIS: Information regarding depression was added to isotretinoin labeling in 1998 following a series of case reports and submitted to the MedWatch system. CONCLUSIONS: Although a causal relationship may exist between isotretinoin and psychiatric illness in adolescents and young adults, this has not been demonstrated in the literature. Until evidence establishes a presence or lack of causality, prescribers should exercise caution when treating adolescents and young adults with isotretinoin. |
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Authors:
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Shelly J Enders; Jason M Enders |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Annals of pharmacotherapy Volume: 37 ISSN: 1060-0280 ISO Abbreviation: Ann Pharmacother Publication Date: 2003 Jul-Aug |
Date Detail:
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Created Date: 2003-07-04 Completed Date: 2003-09-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203131 Medline TA: Ann Pharmacother Country: United States |
Other Details:
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Languages: eng Pagination: 1124-7 Citation Subset: IM |
Affiliation:
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Division of Pharmacy Practice, St. Louis College of Pharmacy, St. Louis, MO 63110-1088, USA. senders@stlcop.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Affect / drug effects Clinical Trials as Topic Depression / chemically induced, epidemiology, psychology Humans Isotretinoin / adverse effects* Keratolytic Agents / adverse effects* Mental Disorders / chemically induced*, epidemiology Risk Assessment |
| Chemical | |
Reg. No./Substance:
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0/Keratolytic Agents; 4759-48-2/Isotretinoin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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