Document Detail


Isotretinoin as a treatment for axillary granular parakeratosis.
MedLine Citation:
PMID:  17725066     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Granular parakeratosis is a condition presenting with hyperkeratotic plaques and papules that are confined to intertriginous body sites. The exact etiology is unknown, but chemical and mechanical irritation and a moist environment are potential factors. Numerous treatments have been attempted, yielding variable results. We present a case of axillary granular parakeratosis, previously unresponsive to topical treatment, that resolved after a 2-week regimen of isotretinoin. We conclude that treatment of axillary granular parakeratosis with isotretinoin is rapid and effective and should be considered in patients with no other contraindications to isotretinoin.
Authors:
Aaron K Compton; J Mark Jackson
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis; cutaneous medicine for the practitioner     Volume:  80     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-08-29     Completed Date:  2007-09-26     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  55-6     Citation Subset:  IM    
Affiliation:
University of Louisville, Kentucky, USA.
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MeSH Terms
Descriptor/Qualifier:
Axilla
Dermatologic Agents / therapeutic use*
Female
Humans
Isotretinoin / therapeutic use*
Middle Aged
Parakeratosis / drug therapy*
Chemical
Reg. No./Substance:
0/Dermatologic Agents; 4759-48-2/Isotretinoin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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