Document Detail

Isosexual precocious puberty.
MedLine Citation:
PMID:  3331207     Owner:  NLM     Status:  MEDLINE    
Isosexual precocious puberty refers to the appearance of phenotypically appropriate secondary sexual characteristics before age 8 years in girls and before 9 years in boys. Isosexual precocity may be categorized into several subgroups depending upon etiology and clinical course: true and complete isosexual precocity refers to early activation of the intact hypothalamic-pituitary-gonadal axis; pseudo-isosexual precocity is due to sex steroid production which is independent of hypothalamic-pituitary regulation; incomplete forms of isosexual precocity include premature thelarche and premature adrenarche. Etiologic, diagnostic and therapeutic considerations are discussed.
D I Shulman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatrician     Volume:  14     ISSN:  0300-1245     ISO Abbreviation:  Pediatrician     Publication Date:  1987  
Date Detail:
Created Date:  1988-08-26     Completed Date:  1988-08-26     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8511837     Medline TA:  Pediatrician     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  261-9     Citation Subset:  IM    
Department of Pediatrics, University of South Florida College of Medicine, Tampa.
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MeSH Terms
Age Factors
Androgens / secretion
Hypothalamo-Hypophyseal System / metabolism
Pituitary Hormone-Releasing Hormones / therapeutic use
Puberty, Precocious* / classification,  diagnosis,  etiology,  therapy
Sex Characteristics*
Sexual Maturation
Reg. No./Substance:
0/Androgens; 0/Pituitary Hormone-Releasing Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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