Document Detail

Isorhythmic Dissociation--a "physiological" arrhythmia.
MedLine Citation:
PMID:  870580     Owner:  NLM     Status:  MEDLINE    
The behavior of the sino-atrial mechanism in isorhythmic dissociation (IRD) was studied in 21 patients, nine with spontaneous IRD and 12 with artificially pacemaker-induced IRD following electrode placement for heart block. Successive P-P, R-R and P-R intervals and blood pressure (BP) fluctuations were determined and graphically interrelated at control and during IRD. Several features were observed: a. IRD was present only when the independent ventricular rate was close to the atrial; b. P rate oscillations closely followed the P-R interval-dependent BP fluctuations (mean difference 30 mmHg) during IRD. In cardiogenic shock and in severe hypertension IRD could not be achieved easily; c. While during complete dissociation or during 1:1 A-V conduction the sinus rate was remarkably constant (2-4 beats/min variations), it showed marked oscillations (differences of 6-19, mean 13, beats/min) during IRD. All the data and calculations support the theory that in most instances of IRD, the arrhythmia is sustained by the normal physiologically active baroreceptor reflex arc.
E Kaplinsky; R Aronson; H N Neufeld
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  10     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1977 Apr 
Date Detail:
Created Date:  1977-06-30     Completed Date:  1977-06-30     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  179-88     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / etiology,  physiopathology*
Heart Conduction System / physiopathology
Heart Rate
Middle Aged
Pacemaker, Artificial

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