| Isoproterenol stress test during catheterization of patients with coarctation of the aorta. | |
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MedLine Citation:
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PMID: 22299669 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: The exercise test is considered useful in selecting high risk patients withrepaired coarctation of the aorta (CoA), but it is difficult to obtain the cooperation of pediatric patients. The present study determines the feasibility of the isoproterenol stress test (IST) among pediatric patients with CoA. Methods: Thirteen patients with repaired or mild preoperative CoA aged 1-207 (median 13) months underwent 16 ISTs during cardiac catheterization. Peak to peak pressure gradients (PGs) over the coarctation site were measured at baseline and at IST. Balloon angioplasty (BAP) was applied to patients with significant stenosis on angiography. Results: The PG between the ascending and the descending aorta was significantly higher at IST than at baseline (20.5 ± 11.5 vs. 5.6 ± 3.9 mmHg, p < 0.0001). Heart rate, the systolic blood pressure measured at the ascending aorta, and pulse pressure were all significantly higher at IST than at baseline. The PG at IST decreased > 10mmHg in three of six patients after BAP. Conclusions: Significant pressure gradients over the coarctation site develop at IST in pediatric patients with repaired CoA or in preoperative patients with mild coarctation. © 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society. |
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Authors:
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Ki-Sung Kim; Yoshihiko Eryu; Hiroko Asakai; Taiyu Hayashi; Masahide Kaneko; Hitoshi Kato |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-2 |
Journal Detail:
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Title: Pediatrics international : official journal of the Japan Pediatric Society Volume: - ISSN: 1442-200X ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100886002 Medline TA: Pediatr Int Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society. |
Affiliation:
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Division of Cardiology, National Center for Child Health and Development 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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