Document Detail

Isoleucine as a possible bridge between exogenous delivery and terrestrial enhancement of homochirality.
MedLine Citation:
PMID:  22968664     Owner:  NLM     Status:  Publisher    
We report a highly enantioselective oligomerization of isoleucine stereomers in the salt-induced peptide formation reaction under plausibly prebiotic earth conditions. Up to 6.5-fold superiority in reactivity of L-isoleucine was observed, compared to its D-enantiomer, after 14 evaporation cycles in the presence of Cu(2+) and NaCl. Since isoleucine is among the proteinogenic amino acids that were found enantioenriched in meteorites, this present work may further correlate the extraterrestrial delivery and endogenous production of biological homochirality by virtue of a protein constituent rather than the rarely occurring α-methylated amino acids.
Feng Li; Daniel Fitz; Bernd M Rode
Related Documents :
18963314 - Dichlorohydantoin and dibromohydantoin as new oxidimetric titrants in non-aqueous media.
18962934 - Thermometric titration of beta-aryl-alpha-mercaptopropenoic acids and determination of ...
25116734 - Hydro-dehalogenation of alkyl iodides with base-mediated hydrogenation and catalytic tr...
9511454 - Analysis of selected diphosphonic acid derivatives used in treatment of osteoporosis. p...
3090134 - Clinical relevance of gastroduodenal dysfunction in reflux esophagitis.
6345544 - Specific incorporation of selenium into lysine- and glutamate- accepting trnas from esc...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-12
Journal Detail:
Title:  Amino acids     Volume:  -     ISSN:  1438-2199     ISO Abbreviation:  Amino Acids     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9200312     Medline TA:  Amino Acids     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Faculty of Chemistry and Pharmacy, Institute of General, Inorganic and Theoretical Chemistry, University of Innsbruck, Innrain 52a, 6020, Innsbruck, Austria.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Antioxidative peptides: enzymatic production, in vitro and in vivo antioxidant activity and potentia...
Next Document:  Supported oligomethionine sulfoxide and Ellman's reagent for cysteine bridges formation.