Document Detail


Isolation and some properties of acid phosphatase-1(1) from tomato leaves.
MedLine Citation:
PMID:  1368604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An isozyme of acid phosphatase-1, acid phosphatase-1(1), was purified from the leaves of tomato (Lycopersicon esculentum) to homogeneity and characterized. The purified enzyme was homogeneous on polyacrylamide gel electrophoresis with or without sodium dodecyl sulfate. The gel filtration analysis showed that the native molecule had a relative molecular mass of about 61 kilodaltons (kDa). The relative molecular mass of the subunit on gel electrophoresis with sodium dodecyl sulfate was about 32 kDa, indicating that the native form of the enzyme was a homodimer. It was suggested by periodic acid-Schiff staining on the gel that the enzyme was a glycoprotein. The Km for p-nitrophenylphosphate was 2.9 x 10(-3) M. The enzyme had a pH optimum of 4.5 in 0.15 M potassium acetate buffer with p-nitrophenylphosphate as a substrate. This enzyme was activated by divalent metal ions, such as Zn2+, Mg2+, and Mn2+. The N-terminal amino acids were sequenced after the purified enzyme was treated with pyroglutamylpeptidase. It was suggested that the N-terminal amino acid was pyroglutamate.
Authors:
H Tanaka; J I Hoshi; K Nakata; M Takagi; K Yano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Agricultural and biological chemistry     Volume:  54     ISSN:  0002-1369     ISO Abbreviation:  Agric. Biol. Chem.     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1991-05-08     Completed Date:  1991-05-08     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0370452     Medline TA:  Agric Biol Chem     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1947-52     Citation Subset:  B    
Affiliation:
Department of Agricultural Chemistry, University of Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Acid Phosphatase / isolation & purification*,  metabolism
Alleles
Amino Acid Sequence
Hydrogen-Ion Concentration
Kinetics
Molecular Sequence Data
Molecular Weight
Nitrophenols / metabolism
Organophosphorus Compounds / metabolism
Plant Proteins / isolation & purification*
Plants / enzymology*,  genetics
Chemical
Reg. No./Substance:
0/Nitrophenols; 0/Organophosphorus Compounds; 0/Plant Proteins; 330-13-2/nitrophenylphosphate; EC 3.1.3.2/Acid Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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