| Isolation and preliminary biochemical characterization of the gonococcal H.8 antigen. | |
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MedLine Citation:
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PMID: 3097238 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We have presented a method for the extraction and isolation of the gonococcal H.8 antigen. There was no evidence of contamination by other gonococcal proteins, phospholipids, or LPS. The purified H.8 antigen was subjected to preliminary analysis and appeared to be a proteolipid consisting of both protein and lipid components. The amino acid composition was unusual; the peptide portion of the antigen was an alanine and proline-rich molecule that lacked aromatic and sulfur-containing amino acids. The overall amino acid composition is hydrophobic. A lipid constituent was also identified; it was made up of at least two lipid components, which were unique to the H.8 molecule. The chemical nature of the association of the protein and lipid is presently unknown, but it is clearly a tenacious one. |
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Authors:
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W Strittmatter; P J Hitchcock |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of experimental medicine Volume: 164 ISSN: 0022-1007 ISO Abbreviation: J. Exp. Med. Publication Date: 1986 Dec |
Date Detail:
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Created Date: 1987-01-08 Completed Date: 1987-01-08 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985109R Medline TA: J Exp Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 2038-48 Citation Subset: IM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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analysis Antigens, Bacterial / immunology, isolation & purification* Antigens, Surface / immunology, isolation & purification Chromatography, Gas Chromatography, High Pressure Liquid Chromatography, Ion Exchange Lipids / analysis Neisseria gonorrhoeae / immunology* |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Antigens, Bacterial; 0/Antigens, Surface; 0/Lipids |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Exp Med ISSN: 0022-1007 ISSN: 1540-9538 Publisher: The Rockefeller University Press |
Article Information Download PDF  Print publication date: Day: 1 Month: 12 Year: 1986 Volume: 164 Issue: 6 First Page: 2038 Last Page: 2048 ID: 2188499 Publisher Id: 87059653 PubMed Id: 3097238 |
| Isolation and preliminary biochemical characterization of the gonococcal H.8 antigen | |
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