| Isolation and potential existence of side population cells in adult human kidney. | |
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MedLine Citation:
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PMID: 18304230 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The existence of adult stem-like cells such as side population (SP) cells is reported in various kinds of animal tissues, and we recently reported that mice kidney SP cells differentiate into multilineage. However, there has thus far been no report about human kidney SP cells. In the present study, we examined the existence of SP cells in human kidney tissue by using Hoechst 33342 staining and fluorescence-activated cell sorting analysis. We used porcine kidney tissue to optimize the analysis conditions for human tissue, and found that the SP population in human kidney was 1.3%. The existence of SP cells in human kidney suggests that the cells could be good targets for clinical renal regenerative medicine. |
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Authors:
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Toshihiko Inowa; Keiichi Hishikawa; Takumi Takeuchi; Tadaichi Kitamura; Toshiro Fujita |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of urology : official journal of the Japanese Urological Association Volume: 15 ISSN: 1442-2042 ISO Abbreviation: Int. J. Urol. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-28 Completed Date: 2008-06-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440237 Medline TA: Int J Urol Country: Australia |
Other Details:
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Languages: eng Pagination: 272-4 Citation Subset: IM |
Affiliation:
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Department of Urology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Animals Cell Separation* Female Flow Cytometry* Humans Kidney / cytology* Male Middle Aged Stem Cells* Swine |
| Comments/Corrections | |
Comment In:
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Int J Urol. 2008 Mar;15(3):274-5
[PMID:
18304231
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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