Document Detail


Isolation of pathogenic bacteria from induced sputum from hospitalized children with pneumonia in Bangladesh.
MedLine Citation:
PMID:  9972076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A prospective study was carried out on 157 patients admitted to a paediatric hospital in Dhaka, Bangladesh to determine the bacteria present in the induced sputum of paediatric patients with X-ray proven pneumonia. Their ages ranged from 21 days to 11 years; 65 per cent of them were male and 35 per cent were female. The most affected age group was between 6 months and 2 years old. Respiratory secretions produced by induced cough were taken by swab from the oropharynx for culture and smear. The predominant bacteria were Haemophilus influenzae, Streptococcus pneumoniae, Branhamella catarrhalis and Gram-negative bacilli. Serotyping of H. influenzae revealed that 76 per cent were non-typable and 18 per cent were of type b; 23.5 per cent of isolates of H. influenzae were beta-lactamase producing. MIC90 of penicillin against S. pneumoniae and H. influenzae were 0.025 and 3.13 micrograms/ml respectively. Ampicillin, penicillin G (benzylpenicillin), amoxycillin, and gentamicin were administered for the treatment of these patients. All cases were apparently improved, on the basis of clinical evaluation, and discharged from the hospital.
Authors:
Y Utsunomiya; K Ahmed; N Rikitomi; M Ruhulamin; M Hanif; H Masaki; K Kawakami; K Watanabe; S K Saha; T Nagatake
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of tropical pediatrics     Volume:  44     ISSN:  0142-6338     ISO Abbreviation:  J. Trop. Pediatr.     Publication Date:  1998 Dec 
Date Detail:
Created Date:  1999-03-02     Completed Date:  1999-03-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8010948     Medline TA:  J Trop Pediatr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  338-42     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Nagasaki University, Japan.
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MeSH Terms
Descriptor/Qualifier:
Age Distribution
Anti-Bacterial Agents / pharmacology
Bangladesh / epidemiology
Bronchial Provocation Tests
Child
Child, Preschool
Female
Gram-Negative Bacterial Infections / diagnosis*,  drug therapy,  epidemiology
Gram-Positive Bacterial Infections / diagnosis*,  drug therapy,  epidemiology
Humans
Incidence
Infant
Infant, Newborn
Male
Microbial Sensitivity Tests
Pharynx / microbiology
Pneumonia, Bacterial / diagnosis,  drug therapy,  epidemiology,  microbiology*
Prospective Studies
Serotyping
Sex Distribution
Sputum / microbiology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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