Document Detail

Isolation and identification of a neuroactive factor from Lathyrus latifolius.
MedLine Citation:
PMID:  13740946     Owner:  NLM     Status:  MEDLINE    
A neuroactive principle of Lathyrus latifolius has been isolated in crystalline form as a monohydrochloride and has been identified as L-alpha,gamma-diaminobutyric acid. This amino acid has also been found in very high concentration in the toxic seed of Lathyrus sylvestris Wagneri. A structural relationship between this factor, the lathyrus factor from Lathyrus odoratus, and, beta-cyano-L-alanine, a new, synthetic neuroactive amino acid nitrile, is pointed out, and a possible biosynthetic pathway relating these is indicated.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Science (New York, N.Y.)     Volume:  134     ISSN:  0036-8075     ISO Abbreviation:  Science     Publication Date:  1961 Jul 
Date Detail:
Created Date:  1961-12-01     Completed Date:  1998-11-01     Revised Date:  2011-12-02    
Medline Journal Info:
Nlm Unique ID:  0404511     Medline TA:  Science     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  188-90     Citation Subset:  OM    
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MeSH Terms
Cyanides / chemistry*
Plants / chemistry*
Reg. No./Substance:

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