Document Detail


Isolation and identification of aliphatic short-chain acylcarnitines from beef heart: possible role for carnitine in branched-chain amino acid metabolism.
MedLine Citation:
PMID:  268629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aliphatic acylearnitines isolated from a water-soluble fraction of beef heart have been characterized by gas chromatography and mass spectrometry. The following acyl residues derived from the acylcarnitine fraction were unequivocally identified: acetyl, propionyl, isobutyryl, butyryl, alpha-methylbutyryl, valeryl, isovaleryl, tiglyl, and caproyl. beta-methylcrotonyl and methacrylyl were tentatively identified. This occurrence of considerable quantities of branched-chain acylcarnitines indicates a role for carnitine in branched-chain amino acid metabolism.
Authors:
L L Bieber; Y R Choi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  74     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1977-10-14     Completed Date:  1977-10-14     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2795-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / metabolism
Animals
Carnitine / analogs & derivatives*,  analysis,  metabolism
Carnitine Acyltransferases / metabolism
Cattle
Mass Spectrometry
Myocardium / analysis*
Chemical
Reg. No./Substance:
0/Amino Acids; 541-15-1/Carnitine; EC 2.3.1.-/Carnitine Acyltransferases
Comments/Corrections

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