Document Detail


Isolation from Cussonia barteri of 1'-O-chlorogenoylchlorogenic acid and 1'-O-chlorogenoylneochlorogenic acid, a new type of quinic acid esters.
MedLine Citation:
PMID:  11731915     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1'-O-Chlorogenoylchlorogenic acid and 1'-O-chlorogenoylneochlorogenic acid, a new type of quinic acid esters, have been isolated, in addition to six known quinic acid esters, rutin, and a mixture of saponins, from the methanol extract of Cussonia barteri Seemann (Araliaceae) leaves collected in Cameroon. Structure determination was achieved by NMR, mass, IR, and UV spectroscopy. All compounds were tested for inhibitory activity on 5-lipoxygenase and cyclooxygenase-1, for antimicrobial activity against Bacillus subtilis, Pseudomonas fluorescens, and Cladosporium cucumerinum, and for haemolytic activity.
Authors:
S Papajewski; B Vogler; J Conrad; I Klaiber; G Roos; C U Walter; R Süssmuth; W Kraus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Planta medica     Volume:  67     ISSN:  0032-0943     ISO Abbreviation:  Planta Med.     Publication Date:  2001 Nov 
Date Detail:
Created Date:  2001-12-03     Completed Date:  2002-07-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0066751     Medline TA:  Planta Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  732-6     Citation Subset:  IM    
Affiliation:
Institut für Chemie, Lehrstuhl für Organische Chemie, Universität Hohenheim, Stuttgart, Germany.
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MeSH Terms
Descriptor/Qualifier:
Anti-Infective Agents / chemistry,  isolation & purification*,  therapeutic use
Araliaceae / chemistry*
Biological Assay
Cameroon
Humans
Magnetic Resonance Spectroscopy
Mass Spectrometry
Medicine, African Traditional
Molecular Structure
Phytotherapy
Plant Leaves / chemistry
Quinic Acid / analogs & derivatives,  chemistry,  isolation & purification*,  therapeutic use
Structure-Activity Relationship
Chemical
Reg. No./Substance:
0/1'-O-chlorogenoylchlorogenic acid; 0/1'-O-chlorogenoylneochlorogenic acid; 0/Anti-Infective Agents; 77-95-2/Quinic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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