Document Detail


Isolation of dealanylalahopcin, a new amino acid, and its biological activity.
MedLine Citation:
PMID:  4008327     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new amino acid, dealanylalahopcin, was isolated from a culture filtrate of Streptomyces albulus subsp. ochragerus; it was also formed by the enzymatic hydrolysis of alahopcin using microbial alpha-amino acid ester hydrolase. The amino acid was obtained as colorless needles and its molecular formula is C6H10N2O5. It showed very weak antibacterial activity against Gram-positive and Gram-negative bacteria, and weak inhibitory activity against the collagen prolylhydroxylase.
Authors:
E Higashide; T Kanamaru; H Fukase; S Horii
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of antibiotics     Volume:  38     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  1985 Mar 
Date Detail:
Created Date:  1985-08-07     Completed Date:  1985-08-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  296-301     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / isolation & purification*,  pharmacology
Aminobutyric Acids / isolation & purification,  pharmacology
Anti-Bacterial Agents / isolation & purification*,  pharmacology
Bacteria / drug effects
Chemical Phenomena
Chemistry
Hydrolysis
Streptomyces / metabolism*
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Aminobutyric Acids; 0/Anti-Bacterial Agents; 96565-32-1/dealanylalahopcin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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