Document Detail


Isolation and characterization of a new chromosome 8q24.1 band-specific microsatellite polymorphism.
MedLine Citation:
PMID:  10072981     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A clone, containing a 24-dinucleotide (CA)-repeat sequence, was isolated from chromosome 8q24.1 band-specific pUC19 library. It was localized to target chromosome using human-rodent hybrid cell panel. Eleven alleles were estimated from 56 unrelated individuals and the heterozygosity reaches 0.835. Linkage analysis of 11 Chinese pedigrees showed significant evidence for linkage of this new marker to three dinucleotide repeat markers at 8q23-24.1 region, with the most likely position of the marker between D8S85 and D8S199.
Authors:
L Xu; J Xia; Y Tang; Q Pan; L Huang; H Deng
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University     Volume:  22     ISSN:  1000-5625     ISO Abbreviation:  Hunan Yi Ke Da Xue Xue Bao     Publication Date:  1997  
Date Detail:
Created Date:  1999-04-28     Completed Date:  1999-04-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9424769     Medline TA:  Hunan Yi Ke Da Xue Xue Bao     Country:  CHINA    
Other Details:
Languages:  eng     Pagination:  471-4     Citation Subset:  IM    
Affiliation:
National Laboratory of Medical Genetics, Hunan Medical University, Changsha.
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MeSH Terms
Descriptor/Qualifier:
Alleles
Animals
Chromosome Mapping
Chromosomes, Human, Pair 8 / genetics*
Dinucleotide Repeats*
Genomic Library
Humans
Hybrid Cells
Linkage (Genetics)
Microsatellite Repeats*
Polymorphism, Genetic*
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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