Document Detail


Isolation and characterization of mutant Pseudomonas aeruginosa strains unable to assimilate nitrate.
MedLine Citation:
PMID:  6433849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Single-site mutants of Pseudomonas aeruginosa that lack the ability aerobically to assimilate nitrate and nitrite as sole sources of nitrogen have been isolated. Twenty-one of these have been subdivided into four groups by transductional analysis. Mutants in only one group, designated nis, lost assimilatory nitrite reductase activity. Mutants in the other three transductional groups, designated ntmA, ntmB, ntmC, display a pleiotropic phenotype: utilization of a number of nitrogen-containing compounds including nitrite as sole nitrogen sources is impaired. Assimilatory nitrite reductase was shown to be the major route by which hydroxylamine is reduced in aerobically-grown cells.
Authors:
R M Jeter; J L Ingraham
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Archives of microbiology     Volume:  138     ISSN:  0302-8933     ISO Abbreviation:  Arch. Microbiol.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-10-01     Completed Date:  1984-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0410427     Medline TA:  Arch Microbiol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  124-30     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Gene Expression Regulation
Genes*
Genes, Bacterial*
Mutation
NADH, NADPH Oxidoreductases / genetics*
Nitrates / metabolism*
Nitrite Reductases / genetics*,  metabolism
Nitrites / metabolism
Nitrogen / metabolism
Phenotype
Pseudomonas aeruginosa / enzymology,  genetics*,  isolation & purification
Transduction, Genetic
Chemical
Reg. No./Substance:
0/Nitrates; 0/Nitrites; 7727-37-9/Nitrogen; EC 1.6.-/NADH, NADPH Oxidoreductases; EC 1.7.-/Nitrite Reductases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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