Document Detail


Isolation, characterization, and expression of fatty acid binding protein in the liver of Gallus domesticus.
MedLine Citation:
PMID:  2706939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. Fatty acid binding protein (FABP) was isolated from chicken liver cytosol. 2. Apparent molecular weight, pI, functional activity, and hybridization of a rat hFABP cDNA probe with chicken liver mRNA suggest that chicken liver FABP is structurally related to hepatic FABP (hFABP) previously isolated and characterized in the rat. 3. Fatty acids bound to liver FABP affect the electrophoretic nature of FABP. 4. Levels of liver FABP mRNA isolated from chickens at various stages of development parallel developmental alterations in lipid metabolism, being highest in day old chicks and laying hens versus juvenile birds.
Authors:
J E Sewell; S K Davis; P S Hargis
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Comparative biochemistry and physiology. B, Comparative biochemistry     Volume:  92     ISSN:  0305-0491     ISO Abbreviation:  Comp. Biochem. Physiol., B     Publication Date:  1989  
Date Detail:
Created Date:  1989-05-30     Completed Date:  1989-05-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984730R     Medline TA:  Comp Biochem Physiol B     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  509-16     Citation Subset:  IM    
Affiliation:
Department of Poultry Science, Texas A & M University System, College Station 77843-2472.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis
Animals
Carrier Proteins / genetics,  isolation & purification,  metabolism*
Chickens
DNA / genetics
Fatty Acid-Binding Proteins
Fatty Acids / metabolism*
Isoelectric Point
Liver / metabolism*
Molecular Weight
Neoplasm Proteins*
Nerve Tissue Proteins*
Nucleic Acid Hybridization
RNA, Messenger / genetics
Rats
Species Specificity
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Carrier Proteins; 0/Fabp4 protein, mouse; 0/Fabp7 protein, rat; 0/Fatty Acid-Binding Proteins; 0/Fatty Acids; 0/Neoplasm Proteins; 0/Nerve Tissue Proteins; 0/RNA, Messenger; 9007-49-2/DNA

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