Document Detail


Isolation, characterization and evolution of a new thermophilic Bacillus licheniformis for lactic acid production in mineral salts medium.
MedLine Citation:
PMID:  21704521     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The high fermentation cost of lactic acid is a barrier for polylactic acid (PLA) to compete with the petrochemical derived plastics. In order to lower the cost of lactic acid, the industry needs a microorganism that can ferment various sugars at high temperature (50°C) and at the same time using low cost mineral salts (MS) medium. One such bacterium, BL1, was isolated at 50°C and identified as Bacillus licheniformis. BL1 can ferment glucose to optically pure l-lactate with a maximum specific productivity of 7.8g/hl in LB medium and 0.7g/hl in MS medium at 50°C. BL1 can also consume 10% and 15% glucose in 20 and 48h, respectively. After serial transfer of BL1 and BL2 in different concentrations of xylose and MS medium respectively, the final mutant BL3 could efficiently ferment glucose and xylose with specific productivity of 1.9g/hl and 1.2g/hl in strict MS medium.
Authors:
Qingzhao Wang; Xueming Zhao; Jauhleene Chamu; K T Shanmugam
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-6-6
Journal Detail:
Title:  Bioresource technology     Volume:  -     ISSN:  1873-2976     ISO Abbreviation:  -     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-6-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9889523     Medline TA:  Bioresour Technol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, People's Republic of China; Department of Microbiology and Cell Science, University of Florida, Gainesville, FL, USA.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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