Document Detail


Isolation and characterization of a double-stranded ribonucleic acid from Penicillium chrysogenum.
MedLine Citation:
PMID:  4322084     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Double-stranded ribonucleic acid has been obtained from cells of the fungus Penicillium chrysogenum. This ribonucleic acid appears to be associated with mycophage and is an efficient inducer of interferon Its. extraction and partial purification are discussed, and evidence for its double-stranded and ribosidal nature is reviewed. The implications of viral nucleic acid in the life processes of fungi are considered.
Authors:
P A Lemke; T M Ness
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of virology     Volume:  6     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1970 Dec 
Date Detail:
Created Date:  1971-03-08     Completed Date:  1971-03-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  813-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Assay
Centrifugation, Density Gradient
Cesium
Chromatography, DEAE-Cellulose
Chromatography, Thin Layer
Deoxyribonucleases / metabolism
Guanine / analysis
Hot Temperature
Interferons / analysis
Mice
Microscopy, Electron
Nucleic Acid Denaturation
Penicillium / analysis*
Peptide Hydrolases / metabolism
Plant Viruses*
RNA* / analysis,  isolation & purification
Ribonucleases / metabolism
Spectrophotometry
Sulfates
Vesicular stomatitis Indiana virus
Chemical
Reg. No./Substance:
0/Sulfates; 63231-63-0/RNA; 73-40-5/Guanine; 7440-46-2/Cesium; 9008-11-1/Interferons; EC 3.1.-/Deoxyribonucleases; EC 3.1.-/Ribonucleases; EC 3.4.-/Peptide Hydrolases
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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