Document Detail


Isolation and characterization of [3H]fucose-labeled glycoproteins from the serum of normal rats and rats bearing Zajdela hepatoma.
MedLine Citation:
PMID:  9566720     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Specific [3H]fucose-labeled glycoproteins were found in the serum of rats bearing Zajdela hepatoma, which possess different isoelectric points in comparison with serum glycoproteins from normal rats. The electrophoretic profile of the serum glycoproteins is significantly altered. There is approximately a 2.5 times increase of [3H]fucose incorporation into serum glycoproteins from rats with an ascitic form of hepatoma, compared with normal rats and to animals bearing a solid form of the tumor (which have a considerably greater survival). Serum fucoproteins identical for the two forms of hepatoma were isolated, as well as glycoproteins strongly specific for each of the forms.
Authors:
D Ivanov; M Antonova; J Stoilov; S Zacharieva; E Gavazova; S Ivanov
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer letters     Volume:  125     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-05-08     Completed Date:  1998-05-08     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  227-31     Citation Subset:  IM    
Affiliation:
Institute of Experimental Pathology and Parasitology, Bulgarian Academy of Sciences, Sofia.
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Proteins / metabolism*
Fucose / metabolism*
Glycoproteins / metabolism*
Liver Neoplasms, Experimental / metabolism*
Rats
Rats, Wistar
Tritium / diagnostic use
Chemical
Reg. No./Substance:
0/Blood Proteins; 0/Glycoproteins; 10028-17-8/Tritium; 3713-31-3/Fucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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