Document Detail


Isolation and characterisation of 8-hydroxy-3Z,5Z-tetradecadienoic acid, a putative intermediate in Pichia guilliermondii gamma-decalactone biosynthesis from ricinoleic acid.
MedLine Citation:
PMID:  12007654     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During a screening procedure for the discovery of a strong gamma-decalactone producer from ricinoleic acid, we observed that the yeast Pichia guilliermondii accumulated transiently 8-hydroxy-3Z,5Z-tetradecadienoic acid 1 during gamma-decalactone biosynthesis in the stationary phase of growth. The structural elucidation of 1 was based on nuclear magnetic resonance, infrared, ultraviolet and gas chromatography-mass spectrometry experiments. The occurrence of 1 is discussed in relation with previously proposed gamma-decalactone biosynthetic pathways.
Authors:
G Iacazio; D Martini; B Faure; M H N'Guyen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  FEMS microbiology letters     Volume:  209     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  2002 Mar 
Date Detail:
Created Date:  2002-05-14     Completed Date:  2002-07-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  57-62     Citation Subset:  IM    
Affiliation:
Laboratoire de Microbiologie, UMR-CNRS 6116, Faculté des Sciences de Saint Jérôme, case 452, Av. Escadrille Normandie-Niemen, 13397 Marseille Cedex 20, France. gilles.iacazio@microbio.u-3mrs.fr
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MeSH Terms
Descriptor/Qualifier:
Chromatography, High Pressure Liquid
Fatty Acids, Unsaturated / isolation & purification*,  metabolism
Gas Chromatography-Mass Spectrometry
Hydroxy Acids / isolation & purification*,  metabolism
Lactones / metabolism*
Nuclear Magnetic Resonance, Biomolecular
Pichia / metabolism*
Ricinoleic Acids / metabolism*
Spectrophotometry, Infrared
Spectrophotometry, Ultraviolet
Chemical
Reg. No./Substance:
0/8-hydroxytetradecadienoic acid; 0/Fatty Acids, Unsaturated; 0/Hydroxy Acids; 0/Lactones; 0/Ricinoleic Acids; 141-22-0/ricinoleic acid; 706-14-9/decan-4-olide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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