Document Detail


Isolation of basic acrosin inhibitor from bull seminal plasma (BUSI II).
MedLine Citation:
PMID:  393604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An acrosin inhibitor was isolated from bull seminal plasma by gel filtration on Sephadex G-50 fine and ion-exchange chromatography on CM-Sephadex. The inhibitor is a basic polypeptide (pl greater than or equal to 10.5) of molecular weight 6 200 (calculated from amino acid composition). Its N-terminal amino group is blocked. The inhibitor is not strictly specific in its effect since it also inhibits trypsin and to a lesser degree chymotrypsin, in addition to bull and boar acrosin.
Authors:
D Cechová; V Jonáková; E Sedláková; O Mach
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Hoppe-Seyler's Zeitschrift für physiologische Chemie     Volume:  360     ISSN:  0018-4888     ISO Abbreviation:  Hoppe-Seyler's Z. Physiol. Chem.     Publication Date:  1979 Dec 
Date Detail:
Created Date:  1980-04-17     Completed Date:  1980-04-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985060R     Medline TA:  Hoppe Seylers Z Physiol Chem     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  1753-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acrosin / antagonists & inhibitors*
Amino Acids / analysis
Animals
Cattle
Chymotrypsin / antagonists & inhibitors
Male
Molecular Weight
Peptides / isolation & purification*,  pharmacology
Protease Inhibitors*
Semen / analysis*,  enzymology
Substrate Specificity
Trypsin Inhibitors
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Peptides; 0/Protease Inhibitors; 0/Trypsin Inhibitors; EC 3.4.21.1/Chymotrypsin; EC 3.4.21.10/Acrosin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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