Document Detail


Isolation of antibacterial fatty acids from Schotia brachypetala.
MedLine Citation:
PMID:  12165344     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In southern Africa, the roots of Schotia brachypetala are used by traditional healers to treat dysentery and diarrhoea. Activity-directed fractionation of the ethanol extract of the dried leaves yielded 9,12,15-octadecatrienoic (linolenic) acid and methyl-5,11,14,17-eicosatetraenoate. These fatty acids displayed antibacterial activity against the Gram-positive bacteria Bacillus subtilis and Staphylococcus aureus and to a lesser extent, against the Gram-negative Escherichia coli and Klebsiella pneumoniae.
Authors:
L J McGaw; A K Jäger; J van Staden
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Fitoterapia     Volume:  73     ISSN:  0367-326X     ISO Abbreviation:  Fitoterapia     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-08-07     Completed Date:  2002-10-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  16930290R     Medline TA:  Fitoterapia     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  431-3     Citation Subset:  IM    
Affiliation:
Research Centre for Plant Growth and Development, School of Botany and Zoology, University of Natal Pietermaritzburg, Private Bag X01, 3209, Scottsville, South Africa.
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MeSH Terms
Descriptor/Qualifier:
Africa, Southern
Anti-Bacterial Agents / isolation & purification*,  pharmacology
Fabaceae / chemistry*
Fatty Acids / isolation & purification,  pharmacology*
Gram-Negative Bacteria / drug effects
Gram-Positive Bacteria / drug effects
Medicine, Traditional
Microbial Sensitivity Tests
Trees
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Fatty Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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