Document Detail

Isolation, Structural Elucidation, MS profiling and Evaluation of Triglyceride Accumulation Inhibitory Effects of Benzophenone C-Glucosides from the Leaves of Mangifera indica L.
MedLine Citation:
PMID:  23368644     Owner:  NLM     Status:  Publisher    
70% ethanol-water extract from the leaves of Mangifera indica L. (Anacardiaceae) was found to show inhibitory effect on triglyceride (TG) accumulation in 3T3-L1 cells. From the active fraction, six new benzophenone C-glucosides, foliamangiferosides A3 (1), A4 (2), C4 (3), C5 (4), C6 (5), and C7 (6) together with 11 known benzophenone C-glucosides (7-17) were obtained. In this paper, the isolation, structure elucidation (1-6) and the MS fragment cleavage pathways of all the 17 isolates were studied. 1-6 showed inhibitory effects on TG and free fatty acid accumulation in 3T3-L1 cells at 10 μM.
Yi Zhang; Lifeng Han; Dandan Ge; Xuefeng Liu; Erwei Liu; Chunhua Wu; Xiumei Gao; Tao Wang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-31
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-2-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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