Document Detail


Isolation of an Acremonium sp. capable of liquefying cross-linked poly(gamma-glutamic acid) hydrogels and the fungal enzyme involved in the disruption of gamma-ray irradiation-mediated cross-linking.
MedLine Citation:
PMID:  18499062     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A microorganism capable of liquefying cross-linked poly(gamma-glutamic acid) (C-L PGA) was isolated and identified to be an Acremonium sp. The fungus produced an enzyme that can disrupt the cross-linkages of C-L PGA generated by gamma-ray irradiation. The enzyme can also liquefy C-L PGA prepared by chemical cross-linkage, suggesting the involvement of ester bonds in the gamma-ray irradiation-mediated cross-linking of PGA.
Authors:
Osamu Matsui; Ken-Ichi Fujita; Hirokazu Nakayama; Makoto Taniguchi; Yutaka Tarui; Eiji Hirasawa; Yoshinosuke Usuki; Toshio Tanaka
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bioscience and bioengineering     Volume:  105     ISSN:  1389-1723     ISO Abbreviation:  J. Biosci. Bioeng.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-05-23     Completed Date:  2008-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888800     Medline TA:  J Biosci Bioeng     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  422-4     Citation Subset:  IM    
Affiliation:
Graduate School of Science, Osaka City University, 3-3-138 Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan.
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MeSH Terms
Descriptor/Qualifier:
Acremonium / enzymology*,  growth & development,  isolation & purification*
Esterases / metabolism*
Fungal Proteins / metabolism*
Gamma Rays*
Hydrogels / chemistry,  metabolism*
Polyglutamic Acid / chemistry,  metabolism*
Chemical
Reg. No./Substance:
0/Fungal Proteins; 0/Hydrogels; 25513-46-6/Polyglutamic Acid; EC 3.1.-/Esterases

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