Document Detail


Isolated unilateral tongue oedema: the adverse effect of angiotensin converting enzyme inhibitors.
MedLine Citation:
PMID:  23320432     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Angiotensin converting enzyme inhibitors (ACEI) are widely used to treat benign hypertension. These drugs are generally well tolerated. Serious side effects such as angio-oedema are very rare. The authors report a 64-year-old Caucasian woman with a history of liver transplant on Mammalian Target Of Rapamycin (mTOR) inhibitor, who attended Emergency department with angio-oedema only on the left side of her tongue. Her airway was patent and she was haemodynamically stable. Trauma was denied. Her physician had 2 days earlier commenced her on Lisinopril for newly diagnosed benign hypertension. Intravenous steroids and anti-histamine were immediately administered. A good response of oedema subsidence was noted. In general, angio-oedema can present in a spectrum of severity. Precipitating factors are often difficult to pre-determine and avoid. Early recognition of risk factors for and diagnosis of angio-oedema can often be life-saving.
Authors:
Edmund Leung; Marcelino Yazbek Hanna; Nadeem Tehami; James Francombe
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-16
Journal Detail:
Title:  Current drug safety     Volume:  -     ISSN:  2212-3911     ISO Abbreviation:  Curr Drug Saf     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101270895     Medline TA:  Curr Drug Saf     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
16 Norton Drive, Warwick, CV34 5FE. ed.leung@doctors.org.uk.
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