| Isolated pulmonary Takayasu arteritis: clinicopathologic characteristics. | |
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MedLine Citation:
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PMID: 8733760 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Involvement of the pulmonary arteries is common in systemic Takayasu arteritis and, in nearly all of the reported cases, the diagnosis has been based solely on clinical and angiographic evaluations of the patients. Isolated pulmonary Takayasu arteritis occurs rarely and can be diagnosed only after histologic examination of the appropriate tissue specimens; five such patients are described herein. The patients were two men and three women. Their age at diagnosis ranged from 25 to 66 years. The initial clinical diagnosis was thromboembolism in two patients, and primary pulmonary hypertension, pulmonary granulomatosis, or pulmonary tumor or sarcoidosis in the remaining three patients, respectively. All five patients underwent surgery for lung resection (three patients) or for reconstruction/bypass of the obstructed pulmonary arteries (two patients). Three types of vascular lesions were observed in the surgical specimens: the classic large-vessel granulomatous giant cell arteritis, a peculiar type of organized thrombus with prominent recanalization and neoangiogenesis, and plexogenic arteriopathy. Thus, the histopathologic findings of pulmonary Takayasu arteritis is distinctive and differs in many aspects from that of systemic Takayasu arteritis. Moreover, the vascular lesions of pulmonary Takayasu arteritis are distinguishable from those of pulmonary hypertension, sarcoidosis, and other types of pulmonary angiitis and granulomatosis. |
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Authors:
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J T Lie |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc Volume: 9 ISSN: 0893-3952 ISO Abbreviation: Mod. Pathol. Publication Date: 1996 May |
Date Detail:
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Created Date: 1997-01-14 Completed Date: 1997-01-14 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8806605 Medline TA: Mod Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 469-74 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of California, Davis, School of Medicine, Sacramento, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Diagnosis, Differential Female Humans Lung / blood supply* Lung Diseases / diagnosis, pathology* Male Pulmonary Artery / pathology* Takayasu Arteritis / diagnosis, pathology* |
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