| Isolated pontine lesion in algid cerebral malaria: clinical features, management, and magnetic resonance imaging findings. | |
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MedLine Citation:
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PMID: 8333575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Malaria, the most important of all tropical diseases, causes approximately one million deaths per year. In Plasmodium falciparum malaria, the organs most affected are the brain, kidneys, lungs, and liver. Cerebral involvement is the most important lethal complication with a mortality rate of up to 50%. We report a patient with malignant, tertian falciparum malaria with an initial parasitemia rate of 60% and severe cerebral, hepatorenal, and pulmonary involvement. In addition to the severe diffuse encephalopathy, an initial neurologic examination showed signs of a pontine lesion that was confirmed by cerebral magnetic resonance imaging. We therefore conclude that cerebral malaria may be responsible for focal neurologic lesions that can be demonstrated by this procedure. |
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Authors:
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A W Kampfl; G G Birbamer; B E Pfausler; H P Haring; E Schmutzhard |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 48 ISSN: 0002-9637 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 1993 Jun |
Date Detail:
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Created Date: 1993-08-19 Completed Date: 1993-08-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 818-22 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, University Hospital, Innsbruck, Austria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Component Transfusion Exchange Transfusion, Whole Blood Female Humans Magnetic Resonance Imaging Malaria, Cerebral / pathology*, therapy Mefloquine / therapeutic use Plasma Pons / pathology* Quinine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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130-95-0/Quinine; 53230-10-7/Mefloquine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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