| Isolated pontine infarcts: etiopathogenic mechanisms. | |
| | |
MedLine Citation:
|
PMID: 16324092 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although there are several clinico-topographical studies of pontine infarcts, few include vascular studies. To clarify the etiopathogenic mechanisms of pontine infarcts we analyzed the vascular findings and their association with MRI lesions. The clinical features and vascular findings on transcranial Doppler (TCD) or MR angiography (MRA) of 67 patients with acute infarcts involving the pons were studied. Functional outcome was assessed by modified Rankin Scale (mRS) scores on admission and 2 months later. Two groups of isolated pontine infarcts were found on the basis of lesion location on MRI, according to the extent or not to the anterior surface of the pons: paramedian pontine infarcts (PPI, n = 36) and lacunar pontine infarcts (LPI, n = 31). Hypertension was the most common vascular risk factor and pure motor syndrome was the most frequent clinical profile in both groups. Basilar artery stenosis found on TCD or MRA was significantly more frequent amongst the PPI group (P < 0.05). On admission and 2 months later, the mRS scores of the PPI group were significantly worse (P < 0.0001) than those of the LPI group. Patients with PPI have a significantly higher frequency of basilar artery stenosis and they have a worse prognosis than patients with LPI. |
| | |
Authors:
|
M E Erro; J G?llego; M Herrera; B Bermejo |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: 12 ISSN: 1351-5101 ISO Abbreviation: Eur. J. Neurol. Publication Date: 2005 Dec |
Date Detail:
|
Created Date: 2005-12-05 Completed Date: 2006-01-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: England |
Other Details:
|
Languages: eng Pagination: 984-8 Citation Subset: IM |
Affiliation:
|
Unidad de Ictus, Servicio de Neurolog?a, Hospital de Navarra, Pomplona, Spain. elena.erro.aguirre@cfnavarra.es |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Blood Vessels / pathology Brain Infarction / etiology*, pathology*, physiopathology Diabetes Complications Female Humans Hypertension / complications Magnetic Resonance Angiography Male Pons / pathology*, radiography Retrospective Studies Risk Factors Ultrasonography, Doppler, Transcranial Vertebrobasilar Insufficiency / complications, epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Sex differences in carpal tunnel syndrome: comparison of surgical and non-surgical populations.
Next Document: A role of TNF-alpha gene variant on juvenile ischemic stroke: a case-control study.