| Isolated or phagocytosed miniature dyskeratotic cells in papilloma virus infection associated with cervical neoplasia. | |
| | |
MedLine Citation:
|
PMID: 1318824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Dyskeratotic cells that occur in squamous cervical epithelium under certain abnormal conditions appear in cervical smears in sheets or aggregates, or as miniature cells, either isolated or phagocytosed. In order to determine the tissue correlates of such cells, 116 cervical biopsies with a histopathologic diagnosis of papillomavirus (HPV) infection were reviewed and compared to previous findings in cytological smears; the patients were 18-65 yr of age. Eighty of the 116 cases had, in addition, cervical intraepithelial neoplasia (CIN). A much higher number of miniature dyskeratotic cells was recorded in the biopsies from patients with both HPV and CIN types of lesions (76.3% of the biopsies had isolated miniature cells and 41.3% showed phagocytosed miniature cells), compared to those with only HPV infection (19.4% with isolated and 5.5% with phagocytosed miniature cells). In addition, in the HPV plus CIN patients, the more advanced the neoplastic lesion, the higher the percentage of cases in which both types of dyskeratocytes are observed. These highly keratinized isolated miniature cells are found in, and are considered to arise from, the deeper layers of the epithelium; when phagocytosed they appear in the center of a concentric arrangement of cells. These cells constitute a pathological entity that can be distinguished from the sheets and aggregates of dyskeratotic cells that come from the superficial layers of parakeratotic epithelia. |
| | |
Authors:
|
R J de Borges; A Montes |
Related Documents
:
|
7219234 - "the critical role of the nucleolus in cell differentiation and stem cell development -... 22521544 - Characterization of sphere-forming cells with stem-like properties from the small cell ... 22293994 - Influence of a 50 hz magnetic field and of all-trans‑retinol on the proli... 22591314 - Accumulation of phosphate and polyphosphate by cryptococcus humicola and saccharomyces ... 18344524 - High-resolution array comparative genomic hybridization of single micrometastatic tumor... 11709544 - Similarities between spinocerebellar ataxia type 7 (sca7) cell models and human brain: ... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Diagnostic cytopathology Volume: 8 ISSN: 8755-1039 ISO Abbreviation: Diagn. Cytopathol. Publication Date: 1992 |
Date Detail:
|
Created Date: 1992-07-22 Completed Date: 1992-07-22 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8506895 Medline TA: Diagn Cytopathol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 222-7 Citation Subset: IM |
Affiliation:
|
Instituto Internacional de Estudios Avanzodos (IDEA), Caracas, Venezuela. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Carcinoma in Situ / pathology Epithelium / pathology Female Humans Middle Aged Papillomaviridae* Phagocytosis Tumor Virus Infections / pathology* Uterine Cervical Neoplasms / pathology* Vaginal Smears |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Closure of upper median sternotomy with resorbable polyglycolic acid sutures
Next Document: Fine-needle aspiration biopsy of Ki-1-positive anaplastic large-cell lymphoma.