Document Detail

Isolated juvenile xanthogranuloma in the bone marrow: report of a case and review of the literature.
MedLine Citation:
PMID:  17378689     Owner:  NLM     Status:  MEDLINE    
We report a case of juvenile xanthogranuloma limited to involvement of the bone marrow in a 6-week-old male infant. Evaluation of the bone marrow was a part of the workup for peripheral blood cytopenia. Examination showed hypercellular marrow with paratrabecular clusters of lipidized histiocytes positive for CD68, CD4, and factor XIII(a) and negative for S100 and CD1a. Clinical and radiological workup showed no associated skin lesions or osseous or visceral involvement. The patient was started on chemotherapy with clinical improvement and gradual decreased bone marrow involvement. The child is alive and well at 16 months of age. This case represents, to the best of our knowledge, the 1st documented case of juvenile xanthogranuloma with isolated bone marrow involvement sparing skin and viscera.
Chimen Kesserwan; Daniel R Boué; Samir B Kahwash
Related Documents :
1481849 - Chondrodysplasia punctata: another possible x-linked recessive case.
683499 - Bilateral optic canal meningiomas: a case report.
7297359 - Radiology of sigmoid volvulus.
2297969 - Barium studies and ileoscopy compared in children with suspected crohn's disease.
12424629 - The glandular odontogenic cyst: clinical and radiological features; review of the liter...
17411909 - Development of an interactive model for teaching emergency pediatric radiography: preli...
15908769 - Lymphocytic gastritis in helicobacter pylori-positive gastric malt lymphoma--report of ...
13895329 - Ammoniacal dermatitis. clinical observations on an efficacious, economical and neglecte...
8123319 - Replantation in general dental practice.
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  10     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-03-23     Completed Date:  2007-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-4     Citation Subset:  IM    
Department of Laboratory Medicine, Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antigens, CD / metabolism
Antigens, CD14 / metabolism
Antineoplastic Agents, Phytogenic / therapeutic use
Bone Marrow / drug effects,  metabolism,  pathology*,  surgery
Factor XIIIa / metabolism
Follow-Up Studies
Receptors, Complement 3b / metabolism
Time Factors
Treatment Outcome
Vimentin / metabolism
Vincristine / therapeutic use
Xanthogranuloma, Juvenile / drug therapy,  metabolism,  pathology*,  radiography
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, CD14; 0/Antineoplastic Agents, Phytogenic; 0/Receptors, Complement 3b; 0/Vimentin; 57-22-7/Vincristine; EC XIIIa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Atypical fibroxanthoma and squamous cell carcinoma of the conjunctiva in xeroderma pigmentosum.
Next Document:  A severely affected female infant with x-linked dominant chondrodysplasia punctata: a case report an...