Document Detail


Isolated juvenile xanthogranuloma in the bone marrow: report of a case and review of the literature.
MedLine Citation:
PMID:  17378689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of juvenile xanthogranuloma limited to involvement of the bone marrow in a 6-week-old male infant. Evaluation of the bone marrow was a part of the workup for peripheral blood cytopenia. Examination showed hypercellular marrow with paratrabecular clusters of lipidized histiocytes positive for CD68, CD4, and factor XIII(a) and negative for S100 and CD1a. Clinical and radiological workup showed no associated skin lesions or osseous or visceral involvement. The patient was started on chemotherapy with clinical improvement and gradual decreased bone marrow involvement. The child is alive and well at 16 months of age. This case represents, to the best of our knowledge, the 1st documented case of juvenile xanthogranuloma with isolated bone marrow involvement sparing skin and viscera.
Authors:
Chimen Kesserwan; Daniel R Boué; Samir B Kahwash
Related Documents :
18925399 - The use of thrombin in the radiology department.
599369 - Subarachnoid haemorrhage of unknown aetiology. a clinical and radiological study of 51 ...
683499 - Bilateral optic canal meningiomas: a case report.
15977009 - Severe osteomalacia due to undiagnosed coeliac disease: three case reports of tunisian ...
3389349 - Rapidly progressive osteoarthrosis of ochronotic origin. a pathologic study.
21063139 - Anatomical variation of mental foramen. a case report.
24312739 - A reclusive foreign body in the airway: a case report and a literature review.
20482769 - Reporting on covariate adjustment in randomised controlled trials before and after revi...
24770509 - Nail psoriasis: a review of the literature.
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  10     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2007 Mar-Apr
Date Detail:
Created Date:  2007-03-23     Completed Date:  2007-05-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-4     Citation Subset:  IM    
Affiliation:
Department of Laboratory Medicine, Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antigens, CD / metabolism
Antigens, CD14 / metabolism
Antineoplastic Agents, Phytogenic / therapeutic use
Biopsy
Bone Marrow / drug effects,  metabolism,  pathology*,  surgery
Factor XIIIa / metabolism
Follow-Up Studies
Humans
Immunohistochemistry
Infant
Male
Receptors, Complement 3b / metabolism
Time Factors
Treatment Outcome
Vimentin / metabolism
Vincristine / therapeutic use
Xanthogranuloma, Juvenile / drug therapy,  metabolism,  pathology*,  radiography
Chemical
Reg. No./Substance:
0/Antigens, CD; 0/Antigens, CD14; 0/Antineoplastic Agents, Phytogenic; 0/Receptors, Complement 3b; 0/Vimentin; 57-22-7/Vincristine; EC 2.3.2.13/Factor XIIIa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Atypical fibroxanthoma and squamous cell carcinoma of the conjunctiva in xeroderma pigmentosum.
Next Document:  A severely affected female infant with x-linked dominant chondrodysplasia punctata: a case report an...