Document Detail

Isolated home hypertension in the morning is associated with target organ damage in patients with type 2 diabetes.
MedLine Citation:
PMID:  16141627     Owner:  NLM     Status:  MEDLINE    
To investigate the relationship between the blood pressure control level and cardiovascular risk in type 2 diabetic patients, we evaluated home blood pressure, office blood pressure, biochemical data, and carotid echographic and echocardiographic findings in 148 patients with type 2 diabetes. According to the criteria for hypertension in the guidelines of the Japanese Society of Hypertension, we classified patients into a normotensive group with home systolic blood pressure in the morning (morning HSBP)<135 mmHg and office systolic blood pressure (OSBP)<140 mmHg, an office hypertension group with a morning HSBP<135 mmHg and OSBP>or=140 mmHg, an isolated home hypertension in the morning group with morning HSBP>or=135 mmHg and OSBP<140 mmHg, and a sustained hypertension group with morning HSBP>or=135 mmHg and OSBP>or=140 mmHg. In the isolated home hypertension in the morning group, the fasting insulin level, urinary albumin excretion, maximum carotid artery intima-media complex thickness, and left ventricular posterior wall thickness were significantly higher and the coefficient of variation for RR intervals was significantly lower than in the normotensive group. These results suggest that isolated home hypertension in the morning is a risk factor for target organ damage in type 2 diabetic patients.
Kazuhiko Sakaguchi; Takahiro Horimatsu; Minoru Kishi; Akihiko Takeda; Yutaka Ohnishi; Takashi Koike; Takashi Fujisawa; Mitsuo Maeda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of atherosclerosis and thrombosis     Volume:  12     ISSN:  1340-3478     ISO Abbreviation:  J. Atheroscler. Thromb.     Publication Date:  2005  
Date Detail:
Created Date:  2005-09-05     Completed Date:  2006-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9506298     Medline TA:  J Atheroscler Thromb     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  225-31     Citation Subset:  IM    
Division of Internal Medicine, the Harima Hospital of the Ishikawajima Harima Heavy Industries Health Insurance Society, Hyogo, Japan.
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MeSH Terms
Blood Pressure Determination
Cardiovascular Diseases / etiology*
Carotid Arteries / ultrasonography
Case-Control Studies
Circadian Rhythm
Diabetes Mellitus, Type 2 / complications*,  metabolism,  ultrasonography
Hypertension / complications*,  metabolism,  ultrasonography
Kidney Diseases / etiology
Middle Aged
Office Visits
Self Care

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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