Document Detail

Isolated hepatosplenic tuberculosis.
MedLine Citation:
PMID:  18522893     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Tuberculosis rarely involves the liver and spleen and when it does so, it is usually associated with disseminated disease. METHOD: We report a patient with isolated tuberculosis of the liver and spleen. RESULTS: A 50-year-old man presented with weakness and loss of weight for two months. CT scan of the abdomen showed multiple small hypodense lesions in the liver and spleen. Image-guided biopsy of liver lesion was inconclusive as it showed normal hepatocytes with interspersed lymphocytes. On laparotomy, the liver and spleen were studded with multiple small nodules. A 5-cm wedge of the liver was resected. Histopathological examination confirmed the diagnosis of tubercular hepatitis. A detailed work-up failed to identify any other focus of tuberculosis. CONCLUSION: Although rare, tuberculosis should also be considered in the differential diagnosis for multiple nodules in the liver and spleen, along with lymphoproliferative diseases and metastatic lesions.
Vinay Kumar; Durgatosh Pandey
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hepatobiliary & pancreatic diseases international : HBPD INT     Volume:  7     ISSN:  1499-3872     ISO Abbreviation:  HBPD INT     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-06-04     Completed Date:  2008-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101151457     Medline TA:  Hepatobiliary Pancreat Dis Int     Country:  China    
Other Details:
Languages:  eng     Pagination:  328-30     Citation Subset:  IM    
Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221005, India.
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MeSH Terms
Diagnosis, Differential
Laparotomy / methods
Middle Aged
Tomography, X-Ray Computed
Tuberculosis, Hepatic / complications*,  diagnosis
Tuberculosis, Splenic / complications*,  diagnosis

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