| Isolated gonadotropin deficiency secondary to glioma in septum pellucidum. | |
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MedLine Citation:
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PMID: 3133864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 21-year-old man, who had had normal sexuality beforehand, noticed a decrease in libido and potency, as well as loss of ejaculation. Endocrine evaluation showed normal serum levels of gonadotropins but a low testosterone level. The response to clomiphene citrate was poor while those to luteinizing hormone-releasing hormone and human chorionic gonadotropin were within normal limits. A tumor found in the septum pellucidum through brain-computerized tomography was resected. Histologically it proved to be a mixed tumor composed of astrocytoma and oligodendroglioma. Three months after the operation the patient had recovered normal sexual functions and endocrine evaluations, including the responsiveness to clomiphene citrate, had been restored. This case suggests the existence of some stimulatory fiber for the secretion of luteinizing hormone in the septum pellucidum. |
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Authors:
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M Kitamura; M Namiki; A Okuyama; N Arita; S Mizutani; T Sonoda |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Urologia internationalis Volume: 43 ISSN: 0042-1138 ISO Abbreviation: Urol. Int. Publication Date: 1988 |
Date Detail:
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Created Date: 1988-08-02 Completed Date: 1988-08-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417373 Medline TA: Urol Int Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 122-4 Citation Subset: IM |
Affiliation:
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Department of Urology and Neurosurgery, Osaka University Hospital, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Astrocytoma / metabolism* Brain Neoplasms / metabolism* Follicle Stimulating Hormone / blood Gonadotropin-Releasing Hormone / deficiency* Humans Luteinizing Hormone / blood Male Oligodendroglioma / metabolism* Septum Pellucidum* Testosterone / deficiency |
| Chemical | |
Reg. No./Substance:
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33515-09-2/Gonadotropin-Releasing Hormone; 58-22-0/Testosterone; 9002-67-9/Luteinizing Hormone; 9002-68-0/Follicle Stimulating Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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