| Isolated cerebral vasculitis associated with rheumatoid arthritis. | |
| | |
MedLine Citation:
|
PMID: 20471884 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Central nervous system involvement in rheumatoid arthritis is infrequent. Inflammatory lesions described in the literature are limited to rheumatoid nodules and vasculitis. We report on a 71-year-old woman who presented with a 1-month history of headache and dysarthria, and who had suffered seropositive rheumatoid arthritis without extra-articular complications, for 15 years. Magnetic resonance imaging showed a high-intensity image in FLAIR-weighted sequences in the right cerebral hemisphere, with meningeal gadolinium enhancement. A brain biopsy revealed necrotizing and lymphocytic vasculitis in the meninges as well as cerebral parenchyma. The patient received treatment with high-dose intravenous methylprednisolone with radiological improvement at 6-month follow-up. She remained neurologically asymptomatic in subsequent years. Three years after the onset of neurological symptoms, she was admitted to the hospital with choluria and jaundice. On the fiftieth day of hospitalization, she died from bronchopneumonia. The autopsy showed no signs of vasculitis. Cerebral vasculitis is an infrequent complication in RA. High-doses of intravenous corticosteroids may be an effective treatment. |
| | |
Authors:
|
Núria Caballol Pons; Núria Montalà; José Valverde; Marta Brell; Isidre Ferrer; Sergio Martínez-Yélamos |
Related Documents
:
|
15163464 - Variable resolution electromagnetic tomography (vareta) in evaluation of compression of... 16682234 - Cerebral perfusion mapping using a robust and efficient method for deconvolution analys... 16833034 - Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopa... 7743234 - Noninvasive central nervous system imaging in sickle cell anemia. a preliminary study c... 15163464 - Variable resolution electromagnetic tomography (vareta) in evaluation of compression of... 8141014 - Digital subtraction in contrast-enhanced mr imaging of the postoperative lumbar spine. |
Publication Detail:
|
Type: Case Reports; Journal Article Date: 2010-05-15 |
Journal Detail:
|
Title: Joint, bone, spine : revue du rhumatisme Volume: 77 ISSN: 1778-7254 ISO Abbreviation: Joint Bone Spine Publication Date: 2010 Jul |
Date Detail:
|
Created Date: 2010-07-13 Completed Date: 2010-10-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100938016 Medline TA: Joint Bone Spine Country: France |
Other Details:
|
Languages: eng Pagination: 361-3 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved. |
Affiliation:
|
Department of Neurology, Hospital Dos de Maig, C/Dos de Maig, 301, 08025 Barcelona, Spain. nuriacaballol@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenal Cortex Hormones
/
therapeutic use Aged Arthritis, Rheumatoid / complications* Dose-Response Relationship, Drug Female Humans Magnetic Resonance Imaging Treatment Outcome Vasculitis, Central Nervous System / diagnosis*, drug therapy, etiology* |
| Chemical | |
Reg. No./Substance:
|
0/Adrenal Cortex Hormones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cefepime-resistant Gram-negative bacteremia in febrile neutropenic patients with hematological malig...
Next Document: Towards a multidimensional patient reported outcome measures assessment: Development and validation ...