Document Detail

Isolated adrenocorticotropin deficiency associated with delirium and takotsubo cardiomyopathy.
MedLine Citation:
PMID:  23243525     Owner:  NLM     Status:  PubMed-not-MEDLINE    
We report a 65-year-old woman with isolated adrenocorticotropic hormone (ACTH) deficiency. The patient was transported to the emergency outpatient department by ambulance complaining of malaise and nausea. Because her laboratory data revealed hyponatremia, we performed endocrinological examinations and diagnosed isolated ACTH deficiency. After admission, she went into a delirious state and suffered from takotsubo cardiomyopathy due to adrenal insufficiency. Replacement therapy with hydrocortisone sufficiently improved her delirium and cardiomyopathy. We conclude that her unstable mental state and myocardial dysfunction were closely related to adrenal insufficiency and suggest that adrenal crisis may cause delirium and Takotsubo cardiomyopathy.
Masanori Murakami; Noriko Matsushita; Rie Arai; Naohiro Takahashi; Ryuki Kawamura; Sayaka Suzuki; Sachio Takekawa; Fumiko Iwashima; Takashi Shibui; Akihiro Hata; Yoshihiro Ogawa; Toshiyuki Horiuchi
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Publication Detail:
Type:  Journal Article     Date:  2012-12-03
Journal Detail:
Title:  Case reports in endocrinology     Volume:  2012     ISSN:  2090-651X     ISO Abbreviation:  Case Rep Endocrinol     Publication Date:  2012  
Date Detail:
Created Date:  2012-12-17     Completed Date:  2012-12-18     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  101576457     Medline TA:  Case Rep Endocrinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  580481     Citation Subset:  -    
Department of Endocrinology and Metabolism, Tokyo Metropolitan Health Medical Treatment Corporation Toshima Hospital, 33-1 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan.
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