| Isocapnic hyperpnoea shortens postanesthetic care unit stay after isoflurane anesthesia. | |
| | |
MedLine Citation:
|
PMID: 20495141 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: We conducted a prospective controlled clinical trial of the effect of isocapnic hyperpnoea (IH) on the times-to-recovery milestones in the operating room (OR) and postanesthetic care unit (PACU) after 1.5 to 3 hours of isoflurane anesthesia. METHODS: Thirty ASA grade I-III patients undergoing elective gynecological surgery were randomized at the end of surgery to either IH or the conventional recovery (control). Six patients with duration of anesthesia of <90 minutes were excluded from the analysis. The anesthesia protocol included propofol, fentanyl, morphine, rocuronium, and isoflurane in air/O(2). Unpaired t tests and analyses of variance were used to test for differences in times-to-recovery indicators between the two groups. RESULTS: The durations of anesthesia in IH and control groups were 140.8 + or - 32.7 and 142 + or - 55.6 minutes, respectively (P = 0.99). The time to extubation was much shorter in the IH group than in the control group (6.6 + or - 1.6 (SD) vs. 13. 6 + or - 3.9 minutes, respectively; P < 0.01). The IH group also had shorter times to eye opening (5.8 + or - 1.3 vs. 13.7 + or - 4.5 minutes; P < 0.01), eligibility for leaving the OR (8.0 + or - 1.7 vs. 17.4 + or - 6.1 minutes; P < 0.01), and eligibility for PACU discharge (74.0 + or - 16.5 vs. 94.5 + or - 14.7 minutes; P < 0.01). There were no differences in other indicators of recovery. CONCLUSION: IH accelerates recovery after 1.5 to 3 hours of isoflurane anesthesia and shortens OR and PACU stay. |
| | |
Authors:
|
Rita Katznelson; Adriaan Van Rensburg; Zeev Friedman; Marcin Wasowicz; George N Djaiani; Ludwik Fedorko; Leonid Minkovich; Joseph A Fisher |
Publication Detail:
|
Type: Journal Article; Randomized Controlled Trial Date: 2010-05-21 |
Journal Detail:
|
Title: Anesthesia and analgesia Volume: 111 ISSN: 1526-7598 ISO Abbreviation: Anesth. Analg. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-28 Completed Date: 2010-08-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1310650 Medline TA: Anesth Analg Country: United States |
Other Details:
|
Languages: eng Pagination: 403-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Anesthesia, Toronto General Hospital, Eaton North 3-453, 200 Elizabeth Street, Toronto, Ontario M5G 2C4, Canada. rita.katznelson@uhn.on.c |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anesthesia Recovery Period* Anesthetics, Inhalation* Female Gynecologic Surgical Procedures Humans Hyperventilation* Isoflurane* Length of Stay* Middle Aged Operating Rooms Prospective Studies Recovery Room* Surgical Procedures, Elective Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Anesthetics, Inhalation; 26675-46-7/Isoflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Osteonecrosis of the Mandible After Laryngoscopy and Endotracheal Tube Placement.
Next Document: Reduced in vivo high-energy phosphates precede adriamycin-induced cardiac dysfunction.