Document Detail


Islet versus pancreas transplantation in type 1 diabetes: competitive or complementary?
MedLine Citation:
PMID:  20830612     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Whole organ pancreas and pancreatic islet transplantation are currently the only forms of clinically available β-cell replacement. Both therapeutic options can provide good glycemic control and prevention or stabilization of diabetic complications, but at the price of permanent immunosuppression. Therefore, the indication for transplantation of type 1 diabetes patients must be balanced carefully and should be restricted to a subgroup of patients with extreme lability of metabolic control and frequent hypoglycemia despite optimal medical therapy.
Authors:
Barbara Ludwig; Stefan Ludwig; Anja Steffen; Hans-Detlev Saeger; Stefan R Bornstein
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current diabetes reports     Volume:  10     ISSN:  1539-0829     ISO Abbreviation:  Curr. Diab. Rep.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-18     Completed Date:  2011-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093791     Medline TA:  Curr Diab Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  506-11     Citation Subset:  IM    
Affiliation:
Department of Medicine III, University Hospital Carl Gustav Carus, Fetscherstr. 74, 01307, Dresden, Germany. barbara.ludwig@uniklinikum-dresden.de
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MeSH Terms
Descriptor/Qualifier:
Diabetes Mellitus, Type 1 / surgery*
Humans
Islets of Langerhans Transplantation*
Pancreas Transplantation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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