Document Detail

Ischemic preconditioning: implications for the geriatric heart.
MedLine Citation:
PMID:  11360839     Owner:  NLM     Status:  MEDLINE    
Ischemic preconditioning is among the most consistent and powerful modes of reducing myocardial infarct size. Although several clinical studies have suggested that the human heart can be preconditioned, controversy exists in both the experimental and clinical literature as to whether the senescent heart can be preconditioned. The authors recently reported that older patients (> or = 60 years of age) in the Thrombolysis in Myocardial Infarction-4 study appeared to benefit from a history of angina prior to acute myocardial infarction. This observation may lead to a clinical counterpart to successful preconditioning in the older heart.
R A Kloner; T Shook; C P Cannon; K Przyklenk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of geriatric cardiology     Volume:  10     ISSN:  1076-7460     ISO Abbreviation:  Am J Geriatr Cardiol     Publication Date:    2001 May-Jun
Date Detail:
Created Date:  2001-05-21     Completed Date:  2001-06-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9215283     Medline TA:  Am J Geriatr Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  145-8; quiz 149-51     Citation Subset:  IM    
Heart Institute, Good Samaritan Hospital, 1225 Wilshire Boulevard, Los Angeles, CA 90017, USA.
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MeSH Terms
Ischemic Preconditioning, Myocardial*
Middle Aged
Myocardial Infarction / therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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