Document Detail


Ischemic myocardial contracture ("stone heart"). A complication of cardiac surgery.
MedLine Citation:
PMID:  1112706     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stone heart or ischemic myocardial contracture is a complication of cardiopulmonary bypass characterized by contracture of the myocardium and inability to obtain cardiac output on manual massage. Stone heart has occurred only during aortic valve replacement and/or coronary artery bypass procedures. Predisposing factors are chronic congestive heart failure and myocardial hypertrophy with fibrosis secondary to longstanding aortic valve disease and/or coronary artery occlusive disease. Although the condition is rare, the outcome is usually fatal. Because of the biochemical and physiological implications of this syndrome, its prevention has been challenging. On the basis of our current concepts, prevention has been afforded by topical and general hypothermia and pretreatment with a small i.v. bolus of propranolol just prior to aortic occlusion. These measures have been utilized in potentially high-risk patients with the predisposition for stone heart and, thus far, the results have been satisfactory. The stone heart syndrome is an entity which should be recognized by all cardiac surgeons. Preventive measures must be aimed at protection of the myocardium during anoxic cardiac arrest.
Authors:
D A Cooley; G J Reul; D C Wukasch
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Israel journal of medical sciences     Volume:  11     ISSN:  0021-2180     ISO Abbreviation:  Isr. J. Med. Sci.     Publication Date:    1975 Feb-Mar
Date Detail:
Created Date:  1975-05-19     Completed Date:  1975-05-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0013105     Medline TA:  Isr J Med Sci     Country:  ISRAEL    
Other Details:
Languages:  eng     Pagination:  203-10     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cardiac Output
Cardiopulmonary Bypass / adverse effects*
Coronary Disease / etiology*,  prevention & control
Endomyocardial Fibrosis / complications
Extracorporeal Circulation / adverse effects*
Heart / physiopathology
Heart Arrest / complications
Heart Failure / complications
Heart Massage
Humans
Hypothermia, Induced
Propranolol / administration & dosage
Chemical
Reg. No./Substance:
525-66-6/Propranolol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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