| Ischemic myocardial contracture ("stone heart"). A complication of cardiac surgery. | |
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MedLine Citation:
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PMID: 1112706 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Stone heart or ischemic myocardial contracture is a complication of cardiopulmonary bypass characterized by contracture of the myocardium and inability to obtain cardiac output on manual massage. Stone heart has occurred only during aortic valve replacement and/or coronary artery bypass procedures. Predisposing factors are chronic congestive heart failure and myocardial hypertrophy with fibrosis secondary to longstanding aortic valve disease and/or coronary artery occlusive disease. Although the condition is rare, the outcome is usually fatal. Because of the biochemical and physiological implications of this syndrome, its prevention has been challenging. On the basis of our current concepts, prevention has been afforded by topical and general hypothermia and pretreatment with a small i.v. bolus of propranolol just prior to aortic occlusion. These measures have been utilized in potentially high-risk patients with the predisposition for stone heart and, thus far, the results have been satisfactory. The stone heart syndrome is an entity which should be recognized by all cardiac surgeons. Preventive measures must be aimed at protection of the myocardium during anoxic cardiac arrest. |
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Authors:
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D A Cooley; G J Reul; D C Wukasch |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Israel journal of medical sciences Volume: 11 ISSN: 0021-2180 ISO Abbreviation: Isr. J. Med. Sci. Publication Date: 1975 Feb-Mar |
Date Detail:
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Created Date: 1975-05-19 Completed Date: 1975-05-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0013105 Medline TA: Isr J Med Sci Country: ISRAEL |
Other Details:
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Languages: eng Pagination: 203-10 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Output Cardiopulmonary Bypass / adverse effects* Coronary Disease / etiology*, prevention & control Endomyocardial Fibrosis / complications Extracorporeal Circulation / adverse effects* Heart / physiopathology Heart Arrest / complications Heart Failure / complications Heart Massage Humans Hypothermia, Induced Propranolol / administration & dosage |
| Chemical | |
Reg. No./Substance:
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525-66-6/Propranolol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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