Document Detail


Ischemic heart disease mortality and PM(3.5) in a cohort of autoworkers.
MedLine Citation:
PMID:  23280679     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Increased risk of ischemic heart disease (IHD) has been associated with particulate matter (PM) from air pollution. Yet evidence of increased risk associated with higher workplace exposures is scant. METHODS: We examined the exposure-response relationship between IHD mortality and PM(3.5) (<3.5 µm diameter) from current and cumulative exposure to straight metalworking fluid in a cohort of 39,412 autoworkers followed from 1941 to 1995. Age, calendar year of follow up, sex, race, and plant were included in each model. RESULTS: To address the decrease in polycyclic-aromatic hydrocarbon (PAH) content in the straight metalworking fluid over time, analyses were stratified by calendar time. Increased risk of IHD mortality was associated with current exposure to PM(3.5) before 1971 and with cumulative exposure to PM(3.5) after 1971. CONCLUSIONS: Results provide modest evidence that occupational exposure to fine PM from straight fluids, especially fluid with higher PAH, may increase the risk of IHD mortality. Am. J. Ind. Med. © 2012 Wiley Periodicals, Inc.
Authors:
Sadie Costello; Erika Garcia; S Katharine Hammond; Ellen A Eisen
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-31
Journal Detail:
Title:  American journal of industrial medicine     Volume:  -     ISSN:  1097-0274     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-1-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Affiliation:
Environmental Health Science, University of California, Berkeley, California. sadie@berkeley.edu.
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