| Ischemic heart disease: metabolic approaches to management. | |
| | |
MedLine Citation:
|
PMID: 15346837 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The number of patients with coronary artery disease and its risk factors is increasing in Western nations. New treatments for these patients may soon include a class of agents known as the metabolic modulators. This group of agents consists of the partial fatty acid oxidation inhibitors trimetazidine and ranolazine, as well as dichloroacetate, which promotes carbohydrate utilization. Metabolic modulators also include the nutriceuticals L-carnitine and D-ribose. The available evidence regarding the benefits of each of these five agents is reviewed. |
| | |
Authors:
|
Daniel F Pauly; Carl J Pepine |
Related Documents
:
|
21670747 - Assessment of left ventricular function in aortic stenosis. 21925837 - The impact of pulmonary regurgitation on right ventricular regional myocardial function... 9211087 - Carvedilol. a reappraisal of its pharmacological properties and therapeutic use in card... 21873337 - Design and preliminary results of the heart function assessment registry trial in saudi... 2655447 - Spontaneous hematoma of a parathyroid adenoma. 6847587 - Effect of brief periods of paced ventricular tachycardia on coronary blood flow in dogs... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Clinical cardiology Volume: 27 ISSN: 0160-9289 ISO Abbreviation: Clin Cardiol Publication Date: 2004 Aug |
Date Detail:
|
Created Date: 2004-09-06 Completed Date: 2004-11-04 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 439-41 Citation Subset: IM |
Affiliation:
|
University of Florida College of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida 32610, USA. paulydf@medicine.ufl.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetanilides Cardiovascular Agents / therapeutic use* Carnitine / therapeutic use Dichloroacetate / therapeutic use Energy Metabolism* Humans Myocardial Ischemia / drug therapy*, metabolism Oxidation-Reduction / drug effects Piperazines / therapeutic use Ribose / therapeutic use Trimetazidine / therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Acetanilides; 0/Cardiovascular Agents; 0/Piperazines; 110445-25-5/ranolazine; 13425-80-4/Dichloroacetate; 50-69-1/Ribose; 5011-34-7/Trimetazidine; 541-15-1/Carnitine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of practice arrangements on physicians' satisfaction.
Next Document: Impact of echocardiography on indications for surgery in chronic mitral and aortic regurgitation.