Document Detail

Ischemic colitis during pregnancy and contraceptive medication.
MedLine Citation:
PMID:  11684827     Owner:  NLM     Status:  MEDLINE    
Ischemic bowel disease is generally considered a disease of the elderly and usually consists of reversible colopathy. Nonocclusive causes of ischemic colitis include low-flow states due to cardiac dysfunction and hypovolemia and use of certain medications including progestational medication. We report 2 cases of ischemic colitis in young women. The first one occurred in a young patient who developed three consecutive episodes of ischemic colitis during her pregnancy, whereas the second woman presented with ischemic colitis in relation with the estrogen use. Each episode had a favorable outcome. Having ruled out an infectious cause, or a low blood flow state and in the absence of known thrombogenic disease, we hypothesized the etiology of these ischemic episodes to a high level of circulating estrogens due to pregnancy in the first case and oral contraceptive medication in the second. Physicians treating hemorrhagic colitis in young women should consider the use of contraceptive medication containing estrogens or pregnancy as possible causes.
J L Frossard; L Spahr; P E Queneau; B Armenian; M A Bründler; A Hadengue
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Digestion     Volume:  64     ISSN:  0012-2823     ISO Abbreviation:  Digestion     Publication Date:  2001  
Date Detail:
Created Date:  2001-10-30     Completed Date:  2001-12-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150472     Medline TA:  Digestion     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  125-7     Citation Subset:  IM    
Copyright Information:
Copyright 2001 S. Karger AG, Basel
Division of Gastroenterology, Geneva University Hospital, Geneva, Switzerland.
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MeSH Terms
Colitis, Ischemic / blood,  etiology*,  pathology
Colon / blood supply,  drug effects,  pathology
Contraceptives, Oral, Hormonal / adverse effects*,  blood
Estrogens / adverse effects*,  blood
Pregnancy Complications / blood*
Reg. No./Substance:
0/Contraceptives, Oral, Hormonal; 0/Estrogens

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