Document Detail


Ischemic colitis as a complication in a patient with steroid-dependent nephrotic syndrome.
MedLine Citation:
PMID:  18038157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the case of a 16-year-old male patient with steroid-dependent nephrotic syndrome who developed ischemic colitis. He was diagnosed as having nephrotic syndrome at 10 years of age and had been administered steroid, cyclosporine A, and mizoribine for 7 years. He presented with severe abdominal pain 5 days after intravenous methylprednisolone pulse therapy; thereafter, massive bloody diarrhea developed. Abdominal ultrasonography and computed tomography revealed a marked thickening of the wall of the transverse colon. Colonoscopy confirmed the diagnosis of ischemic colitis. This is the first report of the development of ischemic colitis in a pediatric patient with nephrotic syndrome.
Authors:
Atsuhiro Yanagisawa; Yoshiyuki Namai; Takashi Sekine; Takashi Igarashi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2007-11-24
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  23     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-03     Completed Date:  2008-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  655-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Ohta Nishinouchi Hospital, Fukushima, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Colitis, Ischemic / diagnosis,  etiology*
Colon / pathology,  radiography,  ultrasonography
Colonoscopy
Cyclosporine / therapeutic use
Diarrhea
Drug Therapy, Combination
Gastrointestinal Hemorrhage
Glucocorticoids / therapeutic use
Humans
Injections, Intravenous
Male
Methylprednisolone / therapeutic use*
Nephrotic Syndrome / complications*,  drug therapy,  pathology
Pulse Therapy, Drug
Chemical
Reg. No./Substance:
0/Glucocorticoids; 59865-13-3/Cyclosporine; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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