| Ischemic time as a predictor of physical recovery in the first months after heart transplantation. | |
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MedLine Citation:
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PMID: 22778997 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Functional results after heart transplantation range from modest to spectacular improvement. Little is known about factors to predict functional result. This study aimed to identify these factors. We present a prospective study including all consecutive transplant recipients (n = 55) in a two-year period whose survival was greater than two months. Perioperative, donor, and recipient issues were systematically analyzed. Exercise capacity was assessed by symptom-limited treadmill exercise testing two months after transplantation. Exercise capacity was classified as satisfactory or poor depending on achieving or not 4.5 METs (metabolic equivalents), respectively. Thirty-three patients (60%) showed a good exercise capacity (>4.5 METs), whereas the remaining twenty-two patients (40%) were unable to exceed this threshold. The variables which correlated with exercise capacity in univariate analysis were recipient age, inotropic treatment, ischemic time, ventricular assist device, etiology, urgent transplant, and INTERMACS score. Among them only recipient age and ischemic time were proved to be correlated with exercise capacity in the multiple regression analysis. Thus, younger patients and those who had received an organ with shorter ischemic time showed greater exercise capacity after transplant. These findings strengthen the trend toward reducing ischemic time as much as possible to improve both survival and clinical recovery. |
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Authors:
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Francisco Buendía-Fuentes; Luis Almenar-Bonet; Luis Martínez-Dolz; Ignacio Sánchez-Lázaro; María Rodríguez-Serrano; Diana Domingo-Valero; María José Sancho-Tello de Carranza; Antonio Salvador-Sanz |
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Publication Detail:
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Type: Journal Article Date: 2012-06-18 |
Journal Detail:
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Title: ISRN cardiology Volume: 2012 ISSN: 2090-5599 ISO Abbreviation: ISRN Cardiol Publication Date: 2012 |
Date Detail:
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Created Date: 2012-07-10 Completed Date: 2012-08-23 Revised Date: 2012-09-26 |
Medline Journal Info:
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Nlm Unique ID: 101566293 Medline TA: ISRN Cardiol Country: Egypt |
Other Details:
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Languages: eng Pagination: 907102 Citation Subset: - |
Affiliation:
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Heart Failure and Transplant Unit, La Fe University Hospital, Boulevar Sur S/N, 46026 Valencia, Spain. |
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